Sensitive Skin Doesn't Always Like Vitamin C—These 16 Serums Are Derm Approved
By now, most of us are using some form of vitamin C in our skincare routine. If you're not yet, you may be missing out on some serious benefits like antioxidant protection, reduced fine lines, and an overall brighter complexion. That being said, we also recognize that ultra-sensitive skin may not take well to a hyper-concentrated vitamin C serum.
If you fall into the latter category, look no further. We hunted down the best derm-approved vitamin C serums for sensitive skin and picked the brains of Marisa Garshick, MD, a board-certified dermatologist located in New York City, and Kaveri Karhade, MD, a board-certified dermatologist located in the Bay Area, for insight on what ingredients to look out for and avoid, especially if you have a condition like rosacea. Keep scrolling for the best vitamin C serums for sensitive skin, backed by dermatologists.
The Best Vitamin C Serums for Sensitive Skin
1. Vichy Liftactiv Brightening and Anti-Aging Vitamin C Serum
This is a top pick for Garshick because it combines 15% L-ascorbic acid with hyaluronic acid to help boost moisture and hydrate the skin. It's also fragrance-free and paraben-free, making it a great option for those with sensitivities.
Pros: Oil-free, fragrance-free, silicone-free, fast-absorbing, non-sticky
Cons: Strong smell, could still be a bit too intense for super-sensitive skin types
Glowing customer review: "I've been using this for a couple of months, and I really like the results. My complexion is smoother, and my dark spots are lighter. Really, overall, it is a nice improvement. I will continue to use it."
2. Skinbetter Science Alto Defense Serum
This is a recommendation from Garshick that combines vitamin C, vitamin E, and 17 other antioxidants to help protect the skin against free radical damage. "[Free radical damage can] lead to signs of aging, including discoloration, fine lines, wrinkles, and collagen breakdown. It also helps to protect the skin against blue light and pollution," she says.
Pros: Infused with vitamins C and E in addition to 17 additional antioxidants, including açaí, turmeric, green tea, and Mediterranean olive; helps improve skin tone; reduces the appearance of skin irritation/redness
Cons: Expensive
Glowing customer review: "I noticed a difference in my skin pigmentation with this serum!"
3. Wander Beauty Sight C-ER Vitamin C Concentrate
Garshick loves this multitasking vitamin C concentrate because it contains niacinamide and Kakadu plum, a potent antioxidant. It's also packed with hyaluronic acid and squalane, which improve overall tone and texture while brightening, hydrating, and improving fine lines.
Pros: Formulated with 20% C-suite complex, hyaluronic acid, squalane, niacinamide, and vitamin E; helps smooth hyperpigmentation and fine lines; budget-friendlier price point
Cons: It could be irritating to super-sensitive skin types
Glowing customer review: "So far, I've used two full containers of this. I didn't think it was doing much for my skin, but then I happened to run out of it and realized all of a sudden my skin didn't look quite as bright as it had been looking before. The only change really was that I ran out of this and hadn't re-purchased. Definitely works, no odd smell, and reasonably priced."
4. CeraVe Skin Renewing Vitamin C Serum
Garshick says this is one of the best drugstore options around for those with sensitive skin. It contains 10% ascorbic acid, ceramides to support the skin barrier, and hyaluronic acid to boost hydration.
Pros: Fragrance-free, formulated with 10% L-ascorbic acid (the purest form of vitamin C) and skin-barrier-protecting ceramides, budget-friendly price point, great for vitamin C beginners
Cons: Packaging could be better
Glowing customer review: "My favorite vitamin C serum! I've been using this for over a year now, and it has vanished my sun spots and given my skin a wonderful glow. I keep it in the fridge and have never had an issues using this product or it turning color. Beautiful and potent vitamin C! Highly recommend!"
5. SkinCeuticals Phloretin CF
For Karhade, this is a great pick for those who err on the side of sensitive and oily. It also contains ferulic acid, a plant-based antioxidant that neutralizes free radicals.
Pros: Evens out skin tone and helps reduce fine lines; great for normal, oily, and combination skin types; alcohol-, fragrance-, and dye-free
Cons: Expensive
Glowing customer review: "I've been using this for a couple of years now. I have always struggled with rosacea, melasma, spots, and big pores. Since I discovered SkinCeuticals, I never have trouble with skin anymore. This makes my skin look so much younger! I'm 43 years old, but I always get to hear that I look at least ten years younger."
6. SkinCeuticals C E Ferulic
Karhade also recommends this cult-favorite vitamin C serum for those with dry, sensitive skin.
Pros: Clinically proven to evens all skin tone by up to 20% and reduces the appearance of fine lines by up to 24%, fragrance- and dye-free, especially great for normal and mature skin types
Cons: Expensive, can cause irritation in some skin types, strong smell
Glowing customer review: "My skin is noticeably brighter, and the sun spots on my forehead are barely visible now. My skin is clear, and I am actually somewhat comfortable not wearing makeup for the first time in years."
7. L'Oréal Revitalift Derm Intensives Vitamin C Serum
L'Oréal tops Karhade's list of best drugstore brands. This 10% vitamin C serum is on the gentler side but still gets the job done.
Pros: Great for vitamin C beginners; dermatologist validated for efficacy and safety; protectively sealed in an airtight metal tube to minimize UV and oxygen exposure; fragrance-free; budget-friendly
Cons: Some reviewers say the packaging can be troublesome and easily damaged after multiple uses
Glowing customer review: "I'm on my second tube, and so far, I really like this product. I saw a huge improvement in my skin overall, especially with fine lines and scars."
8. TruSkin Naturals Vitamin C Serum
Top-rated and highly revered on Amazon is TruSkin Naturals' vitamin C serum. It contains other soothing ingredients like aloe vera and jojoba oil, making it a great option for those with delicate skin.
Pros: Infused with a blend of vitamin C, hyaluronic acid, vitamin E, and aloe vera; highly stable thanks to sodium ascorbyl phosphate, which helps maintain potency while preventing skin irritation; fragrance-free
Cons: Dry skin that needs more hydration will need to layer a moisturizer on top
Glowing customer review: "I found this serum in March of 2023. I wanted a serum that would take away my age spots. I immediately really liked how it felt on my skin, and my skin just drank it up. I have dry skin, and in the winter, it would look dry and flaky when I put on foundation. But, ever since I started using this serum, it's really hydrated my skin, and I have a glow to my face. I loved it so much and will continue to re-purchase."
9. Obagi Medical Professional-C Serum 15%
Another favorite of Karhade, this Obagi serum is suitable for all skin types and penetrates deeply into the skin.
Pros: Formulated with 15% L-ascorbic acid, helps fade hyperpigmentation, affordable price point
Cons: Results are slower than serums with higher concentration of L-ascorbic acid
Glowing customer review: "I've tried a whole bunch of different vitamin C serums, typically ones that were less pricey and/or had other (good) ingredients mixed in, such as vitamin E. However, I always end up coming back to this one as it delivers the best results. Given that the ingredient list is so minimal, it makes sense why it's potent and why it works. I get hyperpigmentation quite easily, usually from the odd acne spot that crops up here and there, and this serum always fades them like a charm."
10. ArtNaturals Anti-Aging Vitamin C Serum
Hyaluronic acid and vitamin E are additional ingredients in this serum that really suit sensitive complexions. It does, however, contain 20% vitamin C, so keep that in mind if your skin has an extra-low tolerance.
Pros: Formulated with vitamin C, hyaluronic acid, and vitamin E; helps smooth fine lines, wrinkles, age, and sun spots; no greasy residue; great price; gentle formula
Cons: Some reviewers note the formula has a runnier consistency
Glowing customer review: "I really like this serum, as it's not too liquid-y. This is a good addition to my morning skin routine. After a few weeks, I have noticed my skin looking a little brighter, even with winter around the corner!"
11. Mario Badescu Vitamin C Serum
This gentle but powerful serum also contains collagen and hyaluronic acid for a youthful boost.
Pros: Ideal for combination, oily, and dry skin types; vitamin C infused with collagen; affordable price point; great for beginners
Cons: Packaging could be better
Glowing customer review: "This product literally gives me a glowing face the whole day. I use the Mario Badescu seaweed cleansing lotion with a cotton pad, then the Mario Badescu facial spray, and while my face is wet, I rub in this serum. And boom! Magic. My face looks hydrated all day!"
12. Summer Fridays CC Me Vitamin C Serum
The addition of squalane and a peptide complex make this vitamin C serum well worth your time if you have sensitive skin.
Pros: Treats dark spots, fine lines, wrinkles, and uneven texture; formulated with 3-O ethyl ascorbic acid, niacinamide, and squalane
Cons: Could still irritate super-sensitive skin types
Glowing customer review: "I have terrible skin. I mostly just hope products don't make it worse. I have almost finished my first bottle, and I'm impressed. My skin loves it! I can see improvements everywhere with no adverse reactions."
13. La Roche-Posay Pure Vitamin C Face Serum
This 10% serum is another small-but-mighty option that leaves skin feeling soft and fully moisturized. It also soothes skin with mineral-rich La-Roche Posay thermal spring water.
Pros: Formulated with salicylic acid, mineral-rich La-Roche Posay thermal spring water, and vitamin C; can be used on sensitive skin, noncomedogenic; dermatologist and allergy tested; oil-free
Cons: Strong smell
Glowing customer review: "After a recent facial, I was told to get a vitamin C serum and use it every morning. I chose this La Roche-Posay serum; it's a wonderful product and seems to brighten my skin tone."
14. Sunday Riley C.E.O. Glow Vitamin C + Turmeric Face Oil
Sunday Riley's C.E.O. Glow earns a spot for its hydrating oils like jojoba and evening primrose in addition to vitamin C. Turmeric also rounds out the formula to calm inflammation.
Pros: Made with an advanced vitamin C, which is blended with cold-pressed red raspberry and evening-primrose-seed oils and turmeric extract; helps improve skin-tone; great serum for dry skin
Cons: Strong smell
Glowing customer review: "I originally got this as a free sample with another purchase. I used it every morning under my moisturizer for a week straight, and the results were incredible! I'm 37 with dry, acne-prone skin. 2020 did a number on my skin. It looked like it aged ten years in the last ten months! This product not only reversed how bad my skin was looking, but It made it even better than before. The best part is that it doesn't make me break out! This is now a forever staple in my skincare routine."
15. Osea Hyaluronic Sea Serum
If pure ascorbic acid is just too much for your skin, you may want to try using a serum that's rich in ingredients that are high in vitamin C. This hydrating serum from Osea, for example, contains Japanese miru seaweed, which is rich in vitamins A, C, E, and K. It may not deliver the dramatic brightening results you'd see with an ascorbic acid serum, but over time, your skin will definitely look healthier and more hydrated. This is one of my personal favorite hydrating serums and it does give your skin a fresh, dewy glow.
Pros: Absorbs quickly; infused with two molecular weights of hyaluronic acid, seaweed, and snow mushroom; clinically and dermatologist tested
Cons: Expensive
Glowing customer review: "This is straight up a holy-grail product. It's pricey, but it lasts forever! One bottle will last me five to six months, and I will use it twice a day! If there's one thing you need in your routine—it's this."
16. Philosophy Bouncy Skin Reactivating Serum
With molecule-grafted hyaluronic acid and vitamin C, this formula promotes intense skin hydration and collagen production. Oxygen in the formula also helps boost skin cells to give them energy and vitality. The result is glowing skin sans the irritation.
Pros: Formulated with oxygen and vitamin C, clinically proven to help restore skin radiance and bounce in one week
Cons: Expensive
Glowing customer review: "I loved this so much. It made my skin glow and feel so healthy. It was very lightweight and not sticky like others; it had no scent, which I loved. A little went a long way. I would 100% recommend this. I have combination skin, for reference."
What Types of Vitamin C Should I Prioritize If I Have Sensitive Skin?
For starters, the concentration of your vitamin C serum is key, especially if you have sensitive skin. According Garshick, choosing a serum that's too highly concentrated can cause irritation. "It's best to stick with vitamin C serums that contain L-ascorbic acid between 10% to 20%," she shares. "If you're sensitive, it's best to start with a concentration of 8% to 10% and increase if needed."
Going for a lower concentration isn't the only option, either. There are other forms of vitamin C, like magnesium ascorbyl phosphate (MAP), that can be just as beneficial for delicate skin types. MAP is water soluble and oil loving, so it deeply penetrates the skin. This also makes it less irritating and easier on a sensitive visage. Another important factor to consider when buying the right vitamin C serum for your skin? The product's pH level. "Those with sensitive skin may prefer a vitamin C with a pH that more closely mimics the skin's natural pH," says Garshick. "Often, vitamin C products are formulated to have a low pH to help with stability, but the lower pH can be irritating, so remember this if you have sensitive skin."
Additionally, some vitamin C serums are formulated with other ingredients. This can be either a win or a loss if you're prone to sensitivities. Garshick reports that moisturizing and soothing agents like niacinamide and hyaluronic acid combine well with vitamin C in this case. "These [ingredients] contain other antioxidants, which may help to stabilize and boost results," she adds.
What Should I Avoid?
On the other hand, there are a few things you should avoid when choosing a vitamin C serum for touchy skin. Karhade suggests steering clear of other active ingredients like BHAs, AHAs, and retinol. Adding any of these to the mix may cause a sensitive complexion to teeter on the edge of irritation. Garshick adds that salicylic acid may not pair well with vitamin C either for sensitive skin. Generally, the consensus is that most other acids should be avoided with it.
If you have a skin condition like rosacea, Karhade considers vitamin C a great addition to your routine. As long as you use a gentle formulation, the antioxidant and anti-inflammatory properties can be highly beneficial.
This article was originally published at an earlier date and has since been updated.
Shawna Hudson is a beauty, wellness, lifestyle, and travel writer with over 10 years of experience. She graduated from California State University, Fullerton, with a degree in journalism and has written for other publications such as Bustle, The Zoe Report, Byrdie, Elite Daily, and more. She is currently a beauty writer at Who What Wear and hopes to continue feeding her (completely out-of-control) beauty obsession as long as she can. Stay up to date on her latest finds on Instagram @shawnasimonee.
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