Hold It—This Circadian Rhythm– and Gene-Supporting Skincare Line Just Might Transform Your Skin

As someone who gets the worst sleep (does anyone actually get good sleep these days?), I'm fascinated by the concept of circadian rhythm, which refers to the 24-hour cycle in our body's internal clock. According to the National Institute of General Medical Sciences, most living creatures have circadian rhythms, including animals, plants, and microorganisms. In humans, circadian rhythms impact not only sleep patterns but also other bodily functions, like our hormones, digestion, body temperature, and more. When it gets out of whack, so can everything else—including our skin.

"People who work night shifts have a higher incidence of cancer, inflammatory disease, heart disease, and just higher mortality overall," explains Ava Shamban, MD, a board-certified dermatologist based in Los Angeles with clients including Nicole Kidman, Michelle Yeoh, and Zooey Deschanel. "So then you think, okay, well if it's that important to the body, then something bad is happening to the skin." After delving into the importance of circadian rhythm and its connection to skin health, Shamban was inspired to launch the innovative skincare brand Althaea Skin.

As Shamban explains, the circadian rhythm is connected to "clock genes." (The scientists who discovered them won a Nobel Prize in 2017.) "Clock genes control 50% of the genome," she says. They turn certain genes on during the day and certain ones at night, so it made sense to look at a product that would really support these genes." Shamban worked with veteran cosmetic chemist John Garruto and discovered ingredients that helped support circadian rhythm. These include an ingredient called Circalys, which is sourced from the Ayurvedic botanical green chiretta, and another ingredient called B-Circadin, an extract of the South Korean medicinal plant Lespedeza capitata.

These two ingredients were tested on night-shift workers and showed improved overall skin quality, hydration, eye puffiness, and fine lines and wrinkles. "It was really fascinating that you can reverse some of these changes because you're changing the wake and sleep cycle of the skin," says Shamban. The line includes four skincare products: Day Serum, Awake Eye Gel, Night Serum, and Activation Mask, as well as a device, the C.A.R.A Multi-Modal Tool.

Marie Lodi reviews Althaea Skincare

(Image credit: @marielodiandreakos)

A lot of thought went into building Althaea Skin, from the ingredients to the packaging. According to Louise Butler, the brand's general manager, the formulations are biotechnology derived and meet clean standards. From a sustainability standpoint, each product features refillable and recyclable packaging. "We want healthy skin, but we also want to leave a healthy planet to the next generation and hopefully make good decisions in that way," says Butler.

Now, does the existence of these products justify poor sleep? Obviously not, but it's great that there are products specifically focused on keeping our skin healthy—especially during the nights we can't resist a late-night movie marathon.

Keep reading to learn about my experience using the entire Althaea Skin line.

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Marie Lodi
Freelance Beauty and Fashion Writer/Editor

Marie has covered beauty, fashion, and lifestyle for almost 15 years. She contributes to the beauty section here at Who What Wear. Previously, she was the Looks Editor for Bust Magazine, built the beauty vertical at HelloGiggles as its beauty editor, and was a founding staff writer at Rookie mag, giving fashion advice to teens. Her bylines have appeared in The Cut, Allure, Glamour, The Hollywood Reporter, and more. She was born and raised in Southern California and is based in L.A. Marie is a self-proclaimed costume design nerd and a co-host of Makeover Montage, a podcast about fashion in film and costume design. You'll see her writing about her beauty obsessions: red lipstick, winged eyeliner, pink hair, nail art, and skincare for people over 40. When she's not working, she's playing with her dog, Gnocchi, and writing her style newsletter, Overdressed.